Session 7 – Multi-target-directed ligands in Alzheimer’s disease primarily targeting cholinesterases

18 Sep 2024
10:45-12:35

Session 7 – Multi-target-directed ligands in Alzheimer’s disease primarily targeting cholinesterases

Chair and keynote lecturer: Stanislav Gobec, Ljubljana (Slovenia)

Time Lecture
10:45 Keynote Lecture: Stanislav Gobec, Ljubljana (Slovenia)
Multi-target-directed ligands for potential symptomatic and disease-modifying treatment of Alzheimer’s disease
11:15 Senior Lecture (20 min): Christophe Rochais, Caen (France)
Advancing Neocopride: A Preclinical Candidate Multitarget Directed-Ligand (MTDL) for Neurodegenerative Disease Intervention
11:35 Senior Lecture (20 min): Jose Marco-Contelles, Madrid (Spain)
Cholinesterase-based Inhibitors as Multitarget Small Molecules for the therapy of Alzheimer’s Disease
11:55 Senior Lecture (20 min): Haopeng Sun, Nanjing (China)
Discovery of highly selective butyrylcholinesterase inhibitors for cognitive improvement
12:15 Junior Lecture (10 min flash presentation): Weronika Bagrowska (Poland)
Development of dual pharmacophore models of acetylcholinesterase and human soluble epoxide hydrolase based on local co-solvent molecules distribution
12:25 Junior Lecture (10 min flash presentation): Anže Meden (Slovenia)
Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer’s disease