Session 7 – Translational research of inhibitors of cholinesterases and paraoxonases

18 Sep 2024
08:30-10:20

Session 7 – Translational research of inhibitors of cholinesterases and paraoxonases

Chair and keynote lecturer: Florian Nachon, Brétigny-sur-Orge (France)

Time Lecture
08:30 Keynote Lecture: Florian Nachon, Brétigny-sur-Orge (France)
Pharmaceutical development of butyrylcholinesterase
09:00 Senior Lecture (20 min): Brian Harvey, Potchefstroom (Republic of South Africa)
Selective butyrylcholinesterase inhibition induces antidepressant, pro-cognitive, and antianhedonic effects in a genetic animal model of depression: Role of acetylcholine, ghrelin, and dopamine
09:20 Senior Lecture (20 min): Diego Muñoz-Torrero, Barcelona (Spain)
Leveraging templating effects of acetylcholinesterase for the development of new anti-Alzheimer drug candidates with multiple mechanisms
09:40 Senior Lecture (20 min): Yoko Suzumoto
A novel identification of anti-hypertensive drug Spironolactone as an inhibitor of Paraoxonase 2 lactonase activity
10:00 Junior Lecture (10 min flash presentation)
10:10 Junior Lecture (10 min flash presentation)