Session 2 – Interactions of cholinesterases (AChE and BChE) with substrates, inhibitors and reactivators
Chair and keynote lecturer: Zrinka Kovarik, Zagreb (Croatia)
| Time | Lecture |
|---|---|
| 10:45 | Keynote Lecture: Zrinka Kovarik, Zagreb (Croatia) Evaluating cholinesterase’s interactions with inhibitors and potent reactivators towards efficient treatment in organophosphate poisoning |
| 11:15 | Senior Lecture (20 min): Zoran Radić, La Jolla (USA) Towards the fourth generation of effective uncharged bis-oxime reactivators of organophosphate-inhibited human AChE |
| 11:35 | Senior Lecture (20 min): José Dias, Brétigny sur Orge (France) Development and therapeutic potential of uncharged cholinesterase reactivators |
| 11:55 | Senior Lecture (20 min): Jure Stojan, Ljubljana (Slovenia) Direct Determination of the hydrolysis of poor substrates by human plasma |
| 12:15 | Junior Lecture (10 min flash presentation): Xavier Brazzolotto (France) Inhibition of human butyrylcholinesterase by A-series nerve agents, functional and structural characterization |
| 12:25 | Junior Lecture (10 min flash presentation): Gabriele Horn (Germany) Inhibition kinetics of cholinesterases from various species by the organophosphate CBDP in vitro |