Session 1 – Structure and dynamics of cholinesterases, paraoxonases and phosphotriesterases
Chair and keynote lecturer: Joel L. Sussman, Rehovot (Israel)
| Time | Lecture |
|---|---|
| 08:30 | Keynote Lecture: Joel L. Sussman, Rehovot (Israel) An Unusual α/β Hydrolase Fold Enzyme from an Antarctic Bacterium |
| 09:00 | Senior Lecture (20 min): Frank Raushel (USA) Phosphotriesterase Catalyzed Synthesis of Chiral Precursors to Antiviral Prodrugs |
| 09:20 | Senior Lecture (20 min): Doriano Lamba (Italy) Disentangling the Mechanism Underlying the Covalent MethaneSulfonyl Fluoride Acetylcholinesterase Adduct Formation and Evolvement: Structural and Mechanistic Insights into an Aged-like Inactive Complex Susceptible to Reactivation by a Combination of Nucleophiles. |
| 09:40 | Senior Lecture (20 min): Sofya Lushchekina (Israel) Why is binding of a divalent metal cation to a structural motif containing four carboxylate residues not accompanied by a conformational change? |
| 10:00 | Junior Lecture (10 min flash presentation) |
| 10:10 | Junior Lecture (10 min flash presentation) |